Anthocyanin-Rich Purple Corn Extract Inhibit Diabetes-Associated Glomerular Angiogenesis

Anthocyanin-Rich Purple Corn Extract Inhibit Diabetes-Associated Glomerular Angiogenesis

Diabetic nephropathy (DN) is one of the major diabetic complications and the leading cause of end-stage renal disease. Abnormal angiogenesis results in new vessels that are often immature and play a pathological role in DN, contributing to renal fibrosis and disrupting glomerular failure. Purple corn has been utilized as a daily food and exerts disease-preventive activities. This study was desi...

Purple corn anthocyanins inhibit diabetes-associated glomerular

Purple corn anthocyanins inhibit diabetes-associated glomerular monocyte activation and macrophage infiltration.

Diabetic nephropathy (DN) is one of the major diabetic complications and the leading cause of end-stage renal disease. In early DN, renal injury and macrophage accumulation take place in the pathological environment of glomerular vessels adjacent to renal mesangial cells expressing proinflammatory mediators. Purple corn utilized as a daily food is rich in anthocyanins exerting disease-preventiv...

Antiproliferative and antioxidant properties of anthocyanin-rich extract from açai

An anthocyanin-rich extract, generated from açai (AEA), was investigated for its antioxidant properties and antiproliferative activity against C-6 rat brain glioma cells and MDA-468 human breast cancer cells. AEA has an ORAC value of 2589 lmoles trolox equivalents (TE)/g dried powder and a DPPH radical-scavenging activity of 1208 lmoles TE/g, suggesting that AEA is an exceptional source of natu...

Composition and color stability of anthocyanin-based extract from purple sweet potato

In recent years, public concern about the safety of synthetic pigments led to increasing interest in the development of food colorants from plant tissues, especially from some edible sources. As a group of natural, water-soluble and nontoxic pigments, anthocyanins are widely distributed in plant world and display a variety of colors from orange to purple (Fossen et al., 1998; Janna et al., 2007...